1,1,1 - trifluoroethane; HFC-143a; R143a

1,1,1 - trifluoroethane; HFC-143a; R143a

420-46-2

Airgas

https://www.airgas.com/msds/001099.pdf

2018

Refrigerant HFC gas

gabriel_salierno@uml.edu

Yes

67

7.40

6

7

4

9

6

10

7

10

{"1":{"value":"540000","score":2,"memo":"LC50 Inhalation Gas. Rat. 4 hours."},"5":{"value":"4","score":4,"memo":"https:\/\/haz-map.com\/Diseases\/326"},"10":{"value":"2","score":2},"14":{"value":"2","score":2},"16":{"value":"2","score":2,"memo":"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/9868#section=Pharmacology-and-Biochemistry"},"19":{"value":"4","score":4,"memo":"May cause frostbite"},"20":{"value":"2","score":2},"21":{"value":"2","score":2},"23":{"value":"2","score":2},"24":{"value":"2","score":2},"25":{"value":"2.5","score":6,"memo":"OSHA PEL"},"26":{"value":"2.5","score":4,"memo":"OSHA PEL"},"47":{"value":"6","score":6,"memo":"Neurotoxin - Acute solvent syndrome"},"29":{"value":"4","score":4,"memo":"SDS"},"34":{"value":"2","score":2},"35":{"value":"2","score":2,"memo":"no significant increase of cancer incidence in any organ,"},"36":{"value":"2","score":2,"memo":"there was no significant increase of cancer incidence in any organ"},"38":{"value":"4","score":4,"memo":"There was no significant increase in chromosome aberrations when human lymphocytes were exposed to the substance in vitro"},"39":{"value":"2","score":2},"40":{"value":"2","score":2},"41":{"value":"2","score":2,"memo":"No maternal or developmental toxicity was noted after exposure "},"42":{"value":"2","score":2,"memo":"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/9868#section=Non-Human-Toxicity-Excerpts"},"43":{"value":"2","score":2},"44":{"value":"2","score":2},"50":{"value":"2","score":2,"memo":"QSAR Toolbox data gap filling - Negative from \"[C: 42;Md: 94;P: 1] Data usage options are changed to: Maximal\" for CC(F)(F)F"},"55":{"value":"10","score":10},"58":{"value":"2","score":2},"59":{"value":"2","score":2},"64":{"value":"154","score":2,"memo":"QSAR Toolbox - LC50 Fish Pimephales promelas 96 h - 154 (13.9\u00f71.7E+03) mg\/L from \"[C: 169;Md: 799;P: 1] Subcategorized: Protein binding by OECD \" for CC(F)(F)F"},"65":{"value":"44","score":6,"memo":"EPI Suite"},"66":{"value":"6","score":6},"70":{"value":"11.2","score":2,"memo":"EPI Suite"},"75":{"value":"2","score":2},"76":{"value":"2","score":2},"79":{"value":"8917","score":10,"memo":"EPI Suite"},"77":{"value":"37.5","score":8,"memo":"EPI Suite"},"81":{"value":"75","score":8,"memo":"EPI Suite"},"83":{"value":"8","score":8},"88":{"value":"8","score":8,"memo":"EPI Suite"},"89":{"value":"1.68","score":2,"memo":"HSPiP"},"90":{"value":"6.5","score":2},"92":{"value":"2","score":2},"93":{"value":"3800","score":10},"94":{"value":"10","score":10},"96":{"value":"2","score":2},"99":{"value":"2","score":2},"98":{"value":"2","score":2},"101":{"value":"2","score":2},"100":{"value":"2","score":2},"102":{"value":"6970","score":10,"memo":"EPI suite"},"103":{"value":"10","score":10,"memo":"SDS"},"104":{"value":"10","score":10},"105":{"value":"10","score":10},"108":{"value":"8","score":8,"memo":"SDS Extremely flammable gas"},"109":{"value":"8","score":8,"memo":"SDS"},"110":{"value":"8","score":8,"memo":"SDS"},"111":{"value":"4","score":4},"113":{"value":"","score":""},"114":{"value":"2","score":2},"115":{"value":"2","score":2},"116":{"value":"2","score":2},"117":{"value":"2","score":2,"memo":"SDS"},"135":{"value":"50","score":8,"memo":"SDS Contains gas under pressure"},"144":{"value":"6","score":6},"153":{"value":"10","score":10},"146":{"value":"10","score":10},"147":{"value":"6","score":6},"148":{"value":"10","score":10},"150":{"value":"100","score":2}}

540000

LC50 Inhalation Gas. Rat. 4 hours.

4

https://haz-map.com/Diseases/326

2

2

2

https://pubchem.ncbi.nlm.nih.gov/compound/9868#section=Pharmacology-and-Biochemistry

4

May cause frostbite

2

2

2

2

2.5

OSHA PEL

2.5

OSHA PEL

4

SDS

2

2

no significant increase of cancer incidence in any organ,

2

there was no significant increase of cancer incidence in any organ

4

There was no significant increase in chromosome aberrations when human lymphocytes were exposed to the substance in vitro

2

2

2

No maternal or developmental toxicity was noted after exposure

2

https://pubchem.ncbi.nlm.nih.gov/compound/9868#section=Non-Human-Toxicity-Excerpts

2

2

6

Neurotoxin - Acute solvent syndrome

2

QSAR Toolbox data gap filling - Negative from "[C: 42;Md: 94;P: 1] Data usage options are changed to: Maximal" for CC(F)(F)F

10

2

2

154

QSAR Toolbox - LC50 Fish Pimephales promelas 96 h - 154 (13.9÷1.7E+03) mg/L from "[C: 169;Md: 799;P: 1] Subcategorized: Protein binding by OECD " for CC(F)(F)F

44

EPI Suite

6

11.2

EPI Suite

2

2

37.5

EPI Suite

8917

EPI Suite

75

EPI Suite

8

8

EPI Suite

1.68

HSPiP

6.5

2

3800

10

0

2

2

2

2

2

6970

EPI suite

10

SDS

10

10

8

SDS Extremely flammable gas

8

SDS

8

SDS

4

2

2

2

2

SDS

50

SDS Contains gas under pressure

6

10

6

10

100

0

0

10