Octamethylcyclotetrasiloxane

Octamethylcyclotetrasiloxane

556-67-2

Sigma

https://www.sigmaaldrich.com/US/en/sds/aldrich/235695

2022

Submitted by external request, reviewed by TURI staff

Yes

66

6.40

5

5

10

10

2

6

6

7

{"4":{"value":"36","score":2,"memo":"LC50 Inhalation - Rat - male and female - 4 h - 36 mg\/l - dust\/mist (OECD Test Guideline 403)"},"8":{"value":"4800","score":4,"memo":"LD50 Oral - Rat - male (OECD Test Guideline 401)"},"9":{"value":"4","score":4},"10":{"value":"2","score":2},"12":{"value":"2400","score":4,"memo":"(OECD Test Guideline 402) Remarks: (IUCLID)"},"13":{"value":"4","score":4},"14":{"value":"2","score":2},"17":{"value":"2","score":2},"19":{"value":"2","score":2,"memo":"Maximization Test - Guinea pig Result: Does not cause skin sensitization. (OECD Test Guideline 406)"},"20":{"value":"2","score":2},"21":{"value":"2","score":2},"22":{"value":"2","score":2,"memo":"Eyes - Rabbit Result: No eye irritation (OECD Test Guideline 405)"},"23":{"value":"2","score":2},"24":{"value":"2","score":2},"25":{"value":"10","score":4,"memo":"USA. Workplace Environmental Exposure Levels (WEEL)"},"29":{"value":"6","score":6},"30":{"value":"2","score":2},"33":{"value":"2","score":2},"34":{"value":"2","score":2},"38":{"value":"2","score":2},"41":{"value":"6","score":6,"memo":"SDS"},"42":{"value":"8","score":8},"43":{"value":"6","score":6},"64":{"value":"0.022","score":10,"memo":"flow-through test LC50 - Oncorhynchus mykiss (rainbow trout) - > 0.022 mg\/l - 96 h"},"65":{"value":"0.022","score":10,"memo":"ErC50 - Pseudokirchneriella subcapitata - > 0.022 mg\/l - 96 h (US-EPA)"},"66":{"value":"10","score":10},"67":{"value":"10","score":10},"68":{"value":"10","score":10},"69":{"value":"0.015","score":10,"memo":"flow-through test EC50 - Daphnia magna (Water flea) - > 0.015 mg\/l - 48 h (US-EPA)"},"70":{"value":"0.02","score":10,"memo":"EPI Suite"},"71":{"value":"8","score":8},"72":{"value":"10","score":10},"73":{"value":"10","score":10},"75":{"value":"8","score":8},"79":{"value":"9.4","score":10,"memo":"EPI Suite"},"77":{"value":"37.5","score":8,"memo":"EPI Suite"},"81":{"value":"75","score":8,"memo":"EPI Suite"},"83":{"value":"8","score":8},"84":{"value":"3.7","score":10,"memo":"aerobic - Exposure time 29 d Result: 3.7 % - Not readily biodegradable. (OECD Test Guideline 310)"},"88":{"value":"10","score":10},"89":{"value":"6.488","score":10,"memo":"log Pow: 6.488 at 25.1 \u00b0C (77.2 \u00b0F) - Potential bioaccumulation"},"90":{"value":"12400","score":10,"memo":"Bioconcentration factor (BCF): 12,400 (US-EPA)"},"92":{"value":"10","score":10},"94":{"value":"2","score":2},"97":{"value":"2","score":2},"99":{"value":"2","score":2},"98":{"value":"2","score":2},"101":{"value":"2","score":2},"100":{"value":"2","score":2},"102":{"value":"0.98","score":4,"memo":"1.3 hPa at 20 \u00b0C (68 \u00b0F)"},"104":{"value":"6","score":6},"105":{"value":"6","score":6},"106":{"value":"51","score":6,"memo":"51 \u00b0C (124 \u00b0F) - closed cup - DIN 51755 Part 1"},"107":{"value":"6","score":6},"110":{"value":"4","score":4,"memo":"SDS Violent reactions possible with strong oxidizing agents, alkalines, acids"},"113":{"value":"","score":""},"114":{"value":"2","score":2},"115":{"value":"2","score":2},"117":{"value":"6","score":6},"125":{"value":"6","score":6},"126":{"value":"4","score":4},"131":{"value":"6","score":6},"132":{"value":"4","score":4},"143":{"value":"4","score":4},"146":{"value":"6","score":6},"147":{"value":"6","score":6},"148":{"value":"8","score":8}}

36

LC50 Inhalation - Rat - male and female - 4 h - 36 mg/l - dust/mist (OECD Test Guideline 403)

4800

LD50 Oral - Rat - male (OECD Test Guideline 401)

4

2

2400

(OECD Test Guideline 402) Remarks: (IUCLID)

4

2

2

2

Maximization Test - Guinea pig Result: Does not cause skin sensitization. (OECD Test Guideline 406)

2

2

2

Eyes - Rabbit Result: No eye irritation (OECD Test Guideline 405)

2

2

10

USA. Workplace Environmental Exposure Levels (WEEL)

6

2

2

2

2

6

SDS

8

6

0.022

flow-through test LC50 - Oncorhynchus mykiss (rainbow trout) - > 0.022 mg/l - 96 h

0.022

ErC50 - Pseudokirchneriella subcapitata - > 0.022 mg/l - 96 h (US-EPA)

10

10

10

0.015

flow-through test EC50 - Daphnia magna (Water flea) - > 0.015 mg/l - 48 h (US-EPA)

0.02

EPI Suite

8

10

10

8

37.5

EPI Suite

9.4

EPI Suite

75

EPI Suite

8

3.7

aerobic - Exposure time 29 d Result: 3.7 % - Not readily biodegradable. (OECD Test Guideline 310)

10

6.488

log Pow: 6.488 at 25.1 °C (77.2 °F) - Potential bioaccumulation

12400

Bioconcentration factor (BCF): 12,400 (US-EPA)

10

2

2

2

2

2

2

0.98

1.3 hPa at 20 °C (68 °F)

6

6

51

51 °C (124 °F) - closed cup - DIN 51755 Part 1

6

4

SDS Violent reactions possible with strong oxidizing agents, alkalines, acids

2

2

6

6

4

6

4

4

6

6

8